Living with celiac disease means looking at wellness through a completely different lens. Finding the best supplements for celiac disease can offer real support—especially when the gut needs help absorbing nutrients and the immune system needs steady, gentle balance.

Keep reading to explore key supplements that can nourish from within, support healing, and help the body feel more grounded on a gluten-free path. From restoring what’s been depleted to strengthening digestive health, these tools can make a meaningful difference day to day. 

1. Magnesium: For Gut Healing, Energy, and Nervous System Support

When you’re managing celiac disease, your body is often playing catch-up. Even after going gluten-free, nutrient absorption may still be off—especially when it comes to magnesium. This mineral is one of the most commonly depleted in people with celiac, and its effects touch everything from energy to digestion to sleep.

This mineral works quietly behind the scenes, helping your body relax, your digestion stay regular, and your nervous system stay steady. And when your body’s in recovery mode, magnesium can be one of the best supplements for celiac disease.

What Magnesium Actually Does for You

Celiac disease can leave your body low on magnesium, especially if the damage to your intestines affected absorption. Here’s why your body loves it:

  • Supports muscle function and physical recovery
  • Helps produce energy on a cellular level
  • Keeps bowel movements regular, especially during early gluten withdrawal
  • Calms the nervous system—helping ease anxiety, improve sleep, and support mood

Our Go-To Magnesium for Sensitive Guts

At hol+, we recommend Serenease Magnesium Blend because it delivers the forms your body actually absorbs—without upsetting the stomach. It’s a thoughtful mix of glycinate (great for calming), citrate (gentle on digestion), and malate (ideal for energy). Together, they create a full-spectrum formula that does more than just “cover a gap.” It actively helps your body repair, rebuild, and recharge in a way that feels natural and steady.

2. B Vitamins: The Methylation & Energy Essentials

There’s something really personal about energy—especially when you’re recovering from something like celiac disease. When you feel off, tired, foggy, or moody, there’s often more going on underneath the surface than a missed meal or late bedtime. That’s where B vitamins quietly come in.

After damage to the intestinal lining, your body might be missing the very nutrients that help keep you steady—like B12, B6, and folate. They’re essential for your mood, nerve health, and how well your body detoxes and processes hormones.

Why B Vitamins Are So Essential

When you have celiac disease, poor absorption is a real concern—especially for the B vitamins that help power your cells. Here’s where they really shine:

  • Fueling energy metabolism and mitochondrial function
  • Supporting nerve repair and reducing tingling or numbness
  • Regulating neurotransmitters for more stable mood and mental clarity
  • Driving methylation, which helps with detox, immune resilience, and hormone balance

The Smartest B-Complex for Sensitive Bodies

Our favorite B complex—Boost—includes bioavailable forms your body can actually use, like methylcobalamin (B12), P5P (B6), and methylfolate, blended with magnesium and selenium to support methylation. It’s the kind of supplement that actively helps your energy, mood, and mental clarity rise back up to where they belong.

When your body has been running on low, these are the nutrients that help flip the switch.

3. Zinc: For Gut Lining Repair and Immune Support

Zinc often flies under the radar—but when it’s low, your body feels it in a big way. With celiac disease, absorption takes a hit, and zinc is one of the first nutrients to drop. It’s needed for everything from repairing your gut lining to sharpening your senses.

Zinc plays a huge role in keeping inflammation down, reducing intestinal permeability (aka “leaky gut”), and helping your tissues rebuild from the inside out. If you’ve been healing from gluten damage or feeling extra run down, this might be a missing piece.

  • Helps rebuild and strengthen the intestinal lining
  • Supports immune function and lowers inflammation
  • Aids wound healing (inside and out)
  • Supports taste and smell, which are often affected by deficiencies

Our Gut-Friendly Pick for Daily Zinc

We like to keep things simple and effective. Metagenics Zinc delivers a highly absorbable form of zinc that’s gentle on sensitive guts, with added B6 and amino acids for enhanced uptake. It’s a thoughtful formula in just one small tablet—and one we recommend often.

It’s GI-friendly, smartly dosed, and made for real-life healing. Shop it here and start giving your gut the repair support it deserves.

4. Probiotics: Rebuilding the Gut Microbiome

Your gut microbiome is like a garden—it needs the right balance of living things to thrive. With celiac disease, years of inflammation and damage from gluten can throw that balance way off. Even after going gluten-free, the microbiome often needs a little help reestablishing its healthy rhythm.

That’s where probiotics come in. They help plant the seeds for better digestion, better absorption, and lower inflammation. And when your gut flora gets back to where it needs to be, everything else—energy, mood, even immunity—starts to feel more like home.

What Probiotics Can Do for Your Gut

A well-chosen probiotic can make a real difference, especially during the healing phase after a celiac diagnosis. Look for formulas that are built to restore, not just maintain. Here’s why they’re worth adding:

  • Help repopulate the gut with beneficial bacteria
  • Support digestion and the breakdown of nutrients
  • Reduce inflammation and calm gut-related immune responses
  • Promote stronger gut barrier function

Our Favorite Pick for Deep Gut Repair

We’re big fans of MegaSporeBiotic™ by Microbiome Labs. This isn’t your average probiotic—it’s spore-based, which means it survives the journey through your stomach and actually activates where it’s needed most. It’s designed to recondition the gut, boost microbial diversity, and support a resilient barrier.

It doesn’t require refrigeration, has a long shelf life, and delivers benefits you’ll feel in your digestion and beyond.

5. L-Glutamine: The Gut Wall’s Favorite Fuel

When your gut’s been inflamed for a while, healing takes more than time—it takes the right kind of fuel. L-glutamine is an amino acid that your intestinal cells absolutely love. Think of it as nourishment for your gut lining, especially when it’s been worn down by years of gluten-triggered damage.

If your digestion still feels off—even after going gluten-free—L-glutamine might be the thing that helps smooth everything out. It works quietly but deeply, helping to seal up gaps in the intestinal lining and calm inflammation that lingers long after the gluten is gone.

  • Fuels enterocytes (intestinal cells) so they can repair and regenerate
  • Strengthens the gut lining, which helps prevent leaky gut
  • Reduces inflammation and supports smoother digestion
  • Helps ease lingering bloating, cramping, and discomfort during recovery

Whether you’re in the early healing stages or just looking for that next level of gut support, L-glutamine is a gentle, reliable ally. It’s like giving your digestive system the exact kind of TLC it’s been craving—no guesswork, just real nourishment.

6. Vitamin D: Immune & Mucosal Defense

Vitamin D helps regulate immune responses and supports the mucosal barriers that protect your gut lining. It’s also key for keeping inflammation down and energy up, especially when your body’s been in overdrive from years of immune stress.

Why Vitamin D Is Essential for Celiac Support

This nutrient goes way beyond just “getting sunlight.” For celiac patients, optimizing vitamin D can help restore immune balance and rebuild foundational strength.

  • Regulates immune function and reduces autoimmune overactivity
  • Supports mucosal barrier integrity in the intestines
  • Helps maintain bone mineral density and calcium absorption
  • Can reduce inflammation and improve fatigue

A Daily Boost That’s Easy to Absorb

Metagenics D3 1000 is a simple, high-potency option that delivers vitamin D in its most active form—D3—designed for easy absorption and long-term support. These micro tablets are easy to take and combine beautifully with K2 when needed to help guide calcium into your bones instead of soft tissues.

It’s a smart, steady way to support your immune system and whole-body resilience. Shop D3 1000 here and give your body the sunshine support it’s asking for.

7. Digestive Enzymes: Help Your Body Absorb Nutrients Again

When your gut has spent years under stress, even healthy food can be hard to process. That’s one of the biggest hidden challenges in celiac recovery—your body might be eating clean but still struggling to absorb the goodness. This is where digestive enzymes can make a world of difference.

Enzymes are your gut’s tools for breaking down food so your body can actually use it. After intestinal damage from gluten, it’s common to see sluggish digestion—especially with fats, proteins, and carbs. Supporting that process gives your body space to focus on healing.

How Digestive Enzymes Support Recovery

These enzymes step in and help do the work your gut can’t fully manage yet. The result? Less bloating, better nutrient absorption, and a smoother digestive experience overall.

  • Assist in the breakdown of key macronutrients: proteins, fats, and carbohydrates
  • Support nutrient absorption to rebuild strength and energy
  • Help reduce post-meal bloating and fullness
  • DPP-IV enzyme helps support against incidental gluten exposure

The Blend We Reach For

Pure Encapsulations Digestion GB brings together a unique mix of digestive enzymes, bile salts, taurine, and gentle herbal support for a well-rounded approach to digestion. It’s particularly helpful if your fat digestion has been sluggish or if you feel heavy after meals. With enzymes like lipase, protease, and amylase, this formula helps your body actually use the nutrients you’re working so hard to eat.

Finally, a Whole-Body Approach to Celiac That Makes Sense

You’ve gone gluten-free, read the labels, done the research, maybe even redone your whole kitchen. And still—your body doesn’t feel quite right. The fatigue lingers, your skin is acting up, digestion feels fragile, and your mood is all over the place. If that sounds familiar, you’re not alone. We talk to patients every day who feel like they’re “doing everything right” and still aren’t getting better.

That’s because Celiac disease isn’t just about gluten. It’s about what happens after gluten has done its damage. It’s about the inflammation, the immune system confusion, the nutrient gaps, and the stress your body’s been quietly carrying for years. That’s the part that rarely gets addressed—and that’s exactly where we come in.

At hol+, we believe in giving your body the space, support, and information it needs to heal. We don’t just remove the trigger—we ask what it left behind. Then we build a plan to restore, rebalance, and support every layer of your wellness.

What Functional, Root-Cause Care Looks Like at hol+

Healing from Celiac is deeply personal, and every path looks a little different. Here’s how we build yours:

  • Comprehensive testing gives us a real, data-driven view of what’s going on inside your body. We check nutrient levels (like iron, D, magnesium, and B12), gut health markers, food sensitivities, and immune activity so we’re not guessing.
  • Autoimmune assessments help us identify overlapping conditions, silent inflammation, and hidden triggers that may be keeping your system on edge.
  • Hormone balancing supports the ripple effects Celiac can create—like thyroid dysfunction, adrenal fatigue, and mood swings—especially when you’ve been running on empty for too long.
  • Targeted supplement protocols deliver clean, bioavailable nutrients your body can actually use. We’re careful with forms, dosages, and timing so your gut gets the support it needs without extra strain.
  • Lifestyle therapies like IV nutrient drips, gentle detox support, personalized nutrition counseling, and stress recovery help bring your whole system back into alignment.

We know that Celiac is often diagnosed after a long road of feeling dismissed, misunderstood, or misdiagnosed. That’s why we make sure your experience with us feels different. This is a space where your story matters. Where your symptoms are believed. And where your care is built around your real life.

Whether you’re just starting your gluten-free journey or years into it and still searching for answers, we’re here to help you heal in a way that finally feels complete. With the right plan and the right support, your body knows how to recover. It just needs someone to listen and guide the way.

Feel Strong, Nourished, and Fully Supported Again

If you’re searching for the best supplements for celiac disease, it’s because you’re ready for more than just a restricted diet—you’re ready to feel nourished, energized, and whole again. From magnesium and B vitamins to probiotics and digestive enzymes, every supplement we covered plays a unique role in rebuilding what gluten once disrupted.

At hol+, we don’t believe in bandaid fixes or guesswork. We believe in care that’s personalized, compassionate, and built to get you truly well. If you’re ready to get answers, support your body more deeply, and finally feel like yourself again—we’re here to help. Book your consultation today.

FAQs

What are the best supplements for celiac disease recovery?

The best supplements for celiac disease include magnesium, B vitamins, probiotics, zinc, L-glutamine, vitamin D, and digestive enzymes to support gut repair and nutrient absorption.

Do I need to take supplements if I’m gluten-free?

Often, yes. Even with a clean diet, years of malabsorption can leave gaps in essential nutrients that supplements can help restore more efficiently.

Absolutely. Probiotics support microbiome diversity, reduce inflammation, and strengthen the gut lining—especially after long-term gluten damage.

What makes hol+ different for people with celiac?

We look at the whole picture—gut, hormones, immune system, and lifestyle—and create truly customized plans based on your needs and lab results.

Do you test for vitamin and mineral deficiencies?

Yes, we run detailed lab panels to check for deficiencies like iron, B12, zinc, and magnesium so we can replace only what your body actually needs.

Definitely. We address underlying nutrient imbalances, gut inflammation, and hormone shifts that often drive those symptoms, and we tailor your care accordingly.